Pathobiology Program News

Pathobiology students publish papers

February 28, 2014 · Leave a Comment

Jennifer Wardell has published two first author papers; “Estrogen signaling crosstalk: implications for endocrine resistance in ovarian cancer” – J Steroid Biochem Mol Biol and “Targeting TBP-associated factors in ovarian cancer” – Frontiers Oncology. Jennifer is a 5th year student in Richard Frieman lab.

Yun Gao (Leo) contributions to a project at his previous position has been published  in an article in Cell Death and Disease. The article is titled, “Involvement of miR-9/MCPIP-1 axis in PDGF-BB mediated neurogenesis in neuronal progenitor cells“.

Yun is a 1st year student and is currently in Qian Chen laboratory.


The articles can be accessed  by clicking on the titles and congratulations to you both.

→ Leave a CommentCategories: February 2014

Pathobiology Graduate Alumni, Jennifer Linden’s innovative work on Multiple Sclerosis

January 30, 2014 · Leave a Comment

Jennifer Linden ’12,  researcher at Weill Cornell Medical College in New York  has made headlines for her innovative work on Multiple Sclerosis. Multiple Sclerosis (MS) is an autoimmune disease that affects the brain and spinal cord. According to the work Dr. Linden presented at the 2014 American Society of Microbiology Biodefense and Emerging Diseases Research Meeting held in Washington, DC., MS may be triggered by a toxin produced by  foodborne bacteria. This toxin, known as the epsilon toxin is produced by some strains of the bacterium, Clostridium perfringens. To read more about the potential of this study, click here. Because of its relevance to public health, this work has being picked up by media outlets such as, NBC News and Science Daily, among others

Jennifer was a graduate student in the Pathobiology program, she conducted her thesis work in Joseph Bliss laboratory studying Candidiasis and human neutrophil phagocytosis. Jennifer  graduated in 2012 and is currently a researcher at Weill Cornell Medical College.

→ Leave a CommentCategories: January 2014

Recap of 2013

December 24, 2013 · Comments Off on Recap of 2013

2013 has been a great year for the Pathobiology program and its students. Students have been elected into positions to service the Brown graduate school community, publications have been accrued, research presented, awards and fellowships won, and theses successfully defended. Here’s a recap of some of the highlights from 2013.


Steve Zins, “The human alpha defensin HD5 neutralizes JC polyomavirus infection by reducing ER traffic and stabilizing the viral capsid”. (PMID:24198413)

Jennifer Wardell, “Estrogen-responsiveness of the TFIID subunit TAF4B in the normal mouse ovary and in ovarian tumors”. (PMID: 24068106)

Assetta Benedetta, “5-HT2 receptors facilitate JC polyomavirus entry”. (PMID: 24089568)

Angel Byrd (1st author) and Courtney Johnson, “An Extracellular Matrix–Based Mechanism of Rapid Neutrophil Extracellular Trap Formation in Response to Candida albicans”.

Please note that the above publication list only includes publications first-authored by current Pathobiology graduate students. This list does not reflect all publications garnered by Pathobiology (past and present) students.

2013 Defenses
Caroline Duwaerts, Ph.D. – Steven Gregory. Caroline is currently a post-doctoral fellow at the University of California, San Francisco.
Emma Reilly, Ph.D. – Laurent Brossay. Emma is currently a post-doctoral fellow at University of Rochester.
Noelle Hutchins-Kelso, Ph.D. –Alfred Ayala. Noelle is currently a post-doctoral fellow in Dr. Ayala’s lab.
William Accomando, Ph.D. – Karl Kelsey.
Stacy-Ann Allen-Ramdial, Ph.D. – Walter Atwood. Stacy assumed a position within the IMSD program at Brown as the MARC program assistant. She is moving to Maryland, and intends to pursue a career in public policy.
Chat Jayasuriya, Ph.D. – Qian Chen. Chat is currently a post-doctoral fellow in Dr. Chen’s lab.
Jennifer Maccani, Ph.D. – Karl Kelsey.

Natasha Catlin, Ph.D. – Kim Boekelheide. Natasha is a post-doctoral fellow in the Boekelheide lab.

External fellowships
Steven ZinsF31 NRSA pre-doctoral recipient.
Matthew HirakawaFrederic Poole Gorham pre-doctoral fellow.

National conferences
Over the past year, students presented data from their research in both poster and oral format at the following regional, national, and international conferences: The Society of Toxicology (SOT) national meeting, annual Endocrine Society national conference, American society of Andrology conference, Viruses and cell Gordon research conference (Italy), regional North-East Society of Toxicology meeting, Cold Spring Harbor Asia Conferences on Molecular Basis of Aging and Diseases (China), Advances in Ovarian Cancer Research: From Concept to Clinic Meeting, and the Society for Leukocyte Biology meeting.

Many students received travel awards to off-set the cost of attendance, and some students were awarded prizes in recognition of their outstanding research.

Community outreach
Matt HirakawaGordon School in East Providence.
Anika ToorieHope High School.

Congrats to all on your accomplishments in 2013. We wish you all continued success in 2014 and beyond. Happy Holidays!

Comments Off on Recap of 2013Categories: December 2013